CD3E

gene product
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Knockdown Initiative

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated in Knockdown Initative
Eligible for validation in KDI
1359 antibodies from 37 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeKDWBELICCIPIHCFC
Thermo Fisher Scientific Pierce
43 antibodies
Novus Biologicals
233 antibodies
R&D Systems
7 antibodies
Acris Antibodies GmbH
137 antibodies
antibodies-online
317 antibodies
Proteintech Group
2 antibodies
BioLegend
72 antibodies
Abnova Corporation
37 antibodies