Tissue expression
Cell line expression
Protein structure
EIF4EBP1
Eukaryotic translation initiation factor 4E binding protein 14E-BP1, PHAS-I
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | 60246-1-Ig | 23 references | Monoclonal |
WB
EL
ICC
IHC |
|
Invitrogen Antibodies | AHO1382 | 5 references | Monoclonal |
WB
ICC
FC
OA |
|
Cell Signaling Technology, Inc | 9644 | 5 references | Monoclonal |
WB
ICC
IP
IHC
FC
|
|
antibodies-online | ABIN2869221 | 2 references | Monoclonal |
WB
EL
ICC
IHC
FC
|
|
Boster Biological Technology | M00968 | 1 references | Monoclonal |
WB
ICC
IP
IHC
FC
|
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