Tissue expressionAmygdalaBasal gangliaCerebellumCerebral cortexChoroid plexusHippocampal formationHypothalamusMedulla oblongataMidbrainOlfactory bulbPonsSpinal cordThalamusWhite matterRetinaAdrenal glandParathyroid glandPituitary glandThyroid glandLungEsophagusSalivary glandTongueColonDuodenumRectumSmall intestineStomachGallbladderLiverPancreasKidneyUrinary bladderEpididymisProstateSeminal vesicleTestisBreastCervixEndometriumFallopian tubeOvaryPlacentaVaginaHeart muscleSkeletal muscleSmooth muscleAdipose tissueSkinAppendixBone marrowLymph nodeSpleenThymusTonsil0246810
Cell line expressionAF22GAMGSH-SY5YU-138 MGU-251 MGU-87 MGHTCEpiHTERT-RPE1OE19CACO-2Hep G2CAPAN-2HEK 293NTERA-2RPTEC TERT1RT4PC-3SuSaA-431HaCaTSK-MEL-30WM-115A549HBEC3-KTSCLC-21HAN3-CABEWOEFO-21HeLaHTERT-HME1MCF7SiHaSK-BR-3T-47dHUVEC TERT2TIMEHSkMCASC diffASC TERT1BJBJ hTERT+BJ hTERT+ SV40 Large T+BJ hTERT+ SV40 Large T+ RasG12VFHDF/TERT166HBF TERT88HHSteCLHCN-M2RH-30U-2 OSU-2197DaudiHDLM-2HTEC/SVTERT24-BJURKATKarpas-707MOLT-4REHRPMI-8226U-266/70U-266/84U-698HAP1HELHL-60HMC-1K-562NB-4THP-1U-9370100200300400500600
Protein structure

TNFRSF8

TNF receptor superfamily member 8
CD30, D1S166E, KI-1 
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
More gene data

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                        2632 antibodies from 48 providers.

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                        Invitrogen Antibodies
                        152 antibodies
                        antibodies-online
                        821 antibodies
                        Novus Biologicals
                        301 antibodies
                        R&D Systems
                        23 antibodies
                        Acris Antibodies GmbH
                        38 antibodies
                        Biorbyt
                        137 antibodies
                        Abcepta
                        6 antibodies
                        NovoPro Bioscience Inc.
                        5 antibodies
                        NSJ Bioreagents
                        22 antibodies
                        OriGene
                        167 antibodies
                        GeneTex
                        24 antibodies
                        Abnova Corporation
                        40 antibodies
                        Cell Signaling Technology, Inc
                        8 antibodies
                        Bethyl Laboratories
                        2 antibodies
                        Boster Biological Technology
                        5 antibodies
                        Antibodies.com
                        46 antibodies
                        Abbexa
                        18 antibodies
                        St John's Laboratory
                        9 antibodies
                        Aviva Systems Biology
                        6 antibodies
                        Affinity Biosciences
                        1 antibody
                        Aladdin Scientific
                        4 antibodies
                        Creative Biolabs
                        289 antibodies
                        Cusabio Biotech Co., Ltd
                        2 antibodies
                        Abbkine Scientific Co.Ltd.
                        1 antibody
                        Proteintech Group
                        1 antibody
                        Absolute Antibody
                        19 antibodies
                        BioLegend
                        14 antibodies
                        ProSci
                        9 antibodies
                        Leading Biology
                        19 antibodies
                        Atlas Antibodies
                        4 antibodies
                        eBioscience, An Affymetrix Company
                        10 antibodies
                        RabMAbs
                        2 antibodies
                        Miltenyi Biotec
                        40 antibodies
                        United States Biological
                        56 antibodies
                        Spring Bioscience
                        4 antibodies
                        MyBioSource
                        12 antibodies
                        Sino Biological Inc.
                        7 antibodies
                        Abiocode, Inc.
                        1 antibody
                        Creative Diagnostics
                        17 antibodies
                        GenWay
                        13 antibodies
                        Arigo
                        5 antibodies
                        RayBiotech, Inc.
                        3 antibodies
                        MilliporeSigma / Merck KGaA
                        4 antibodies
                        EMD Millipore
                        1 antibody
                        MedChemExpress LLC
                        1 antibody