CD59

gene product
16.3A5, EJ16, EJ30, EL32, G344, MIC11, MIN1, MIN2, MIN3, MSK21, p18-20
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
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607 antibodies from 25 providers.

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AntibodyRefsTypeKDWBELICCIPIHCFC
antibodies-online
227 antibodies
GeneTex
18 antibodies
Novus Biologicals
79 antibodies
Proteintech Group
1 antibody
Biorbyt
43 antibodies
Abnova Corporation
18 antibodies
Thermo Fisher Scientific Pierce
13 antibodies
R&D Systems
2 antibodies
Aviva Systems Biology
19 antibodies
Acris Antibodies GmbH
31 antibodies
OriGene
4 antibodies
Atlas Antibodies
1 antibody
Bioworld Technology, Inc
1 antibody
RabMAbs
3 antibodies
GenWay
21 antibodies
LifeSpan BioSciences, Inc.
80 antibodies
BioLegend
5 antibodies
RayBiotech, Inc.
6 antibodies
United States Biological
3 antibodies
Abgent
1 antibody
EMD Millipore
2 antibodies
Sigma-Aldrich
3 antibodies
eBioscience, An Affymetrix Company
13 antibodies
BosterBio
1 antibody