PAX5

gene product
BSAP
This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
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251 antibodies from 22 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
84 antibodies
Novus Biologicals
15 antibodies
Thermo Fisher Scientific Pierce
10 antibodies
Abnova Corporation
8 antibodies
Acris Antibodies GmbH
15 antibodies
GeneTex
11 antibodies
LifeSpan BioSciences, Inc.
19 antibodies
Aviva Systems Biology
4 antibodies
RabMAbs
4 antibodies
BioLegend
5 antibodies
Everest Biotech
1 antibody
Creative Biomart
36 antibodies
Cell Signaling Technology, Inc
5 antibodies
Signalway Antibody LLC
1 antibody
Spring Bioscience
8 antibodies
United States Biological
10 antibodies
Abiocode, Inc.
1 antibody
eBioscience, An Affymetrix Company
6 antibodies
GenWay
4 antibodies
Sigma-Aldrich
2 antibodies
R&D Systems
1 antibody
EMD Millipore
1 antibody