CABT-BL7156

antibody from Creative Diagnostics

Targeting: CD27 S152, TNFRSF7, Tp55

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

CABT-BL7156

Provider

Creative Diagnostics

Product name

Anti-CD27 Monoclonal antibody, clone MH.4B20

Antibody type

Monoclonal

Description

CD27 (50 kDa) is a member of the tumor necrosis factor (TNF) receptor superfamily. CD40 and CD30 are also members of the TNF receptor superfamily. The TNF superfamily members are known for the regulation of cell proliferation and death. In contrast to the expression of other TNFR/TNF family members, expression of CD27 and its ligand CD70 is predominantly confined to lymphocytes. High expression levels of CD27 appear to be dependent on proper ligation of antigen receptors. CD70 expression requires additional co-stimulatory and/or pro-inflammatory signals. CD27 is a membranebound receptor, but a soluble form of CD27 is also produced.

Reactivity

Human, Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

MH.4B20

Vial size

50 ug