Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- MAB6446 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB6446, RRID:AB_10677578
- Product name
- CD40 monoclonal antibody, clone HI40a
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against CD40.
- Isotype
- IgG
- Antibody clone number
- HI40a
- Storage
- Store at 4°C. Do not freeze.Aliquot to avoid repeated freezing and thawing.
Submitted references Involvement of mitogen-activated protein kinases and NFkappaB in LPS-induced CD40 expression on human monocytic cells.
CD40-mediated signaling in monocytic cells: up-regulation of tumor necrosis factor receptor-associated factor mRNAs and activation of mitogen-activated protein kinase signaling pathways.
The role of CD40 ligand in costimulation and T-cell activation.
Wu W, Alexis NE, Chen X, Bromberg PA, Peden DB
Toxicology and applied pharmacology 2008 Apr 15;228(2):135-43
Toxicology and applied pharmacology 2008 Apr 15;228(2):135-43
CD40-mediated signaling in monocytic cells: up-regulation of tumor necrosis factor receptor-associated factor mRNAs and activation of mitogen-activated protein kinase signaling pathways.
Pearson LL, Castle BE, Kehry MR
International immunology 2001 Mar;13(3):273-83
International immunology 2001 Mar;13(3):273-83
The role of CD40 ligand in costimulation and T-cell activation.
Grewal IS, Flavell RA
Immunological reviews 1996 Oct;153:85-106
Immunological reviews 1996 Oct;153:85-106
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Supportive validation
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- Abnova Corporation (provider)
- Main image
- Experimental details
- Surface staining of human peripheral blood cells with CD40 monoclonal antibody, clone HI40a (FITC). Cells in the lymphocyte gate were used for analysis.
- Validation comment
- Flow Cytometry