Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN968494 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) (AA 71-187) antibody
- Antibody type
- Monoclonal
- Antigen
- Human CD40
- Description
- Purified from tissue culture supernatant or ascites by affinity chromatography.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 71-187
- Isotype
- IgG
- Antibody clone number
- BC17
- Vial size
- 50 μg
- Concentration
- 250 μg/ml
- Storage
- -20°C
Submitted references TRAF2 deficiency results in hyperactivity of certain TNFR1 signals and impairment of CD40-mediated responses.
Ku in the cytoplasm associates with CD40 in human B cells and translocates into the nucleus following incubation with IL-4 and anti-CD40 mAb.
Arrest of B lymphocyte terminal differentiation by CD40 signaling: mechanism for lack of antibody-secreting cells in germinal centers.
A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas.
Nguyen LT, Duncan GS, Mirtsos C, Ng M, Speiser DE, Shahinian A, Marino MW, Mak TW, Ohashi PS, Yeh WC
Immunity 1999 Sep;11(3):379-89
Immunity 1999 Sep;11(3):379-89
Ku in the cytoplasm associates with CD40 in human B cells and translocates into the nucleus following incubation with IL-4 and anti-CD40 mAb.
Morio T, Hanissian SH, Bacharier LB, Teraoka H, Nonoyama S, Seki M, Kondo J, Nakano H, Lee SK, Geha RS, Yata J
Immunity 1999 Sep;11(3):339-48
Immunity 1999 Sep;11(3):339-48
Arrest of B lymphocyte terminal differentiation by CD40 signaling: mechanism for lack of antibody-secreting cells in germinal centers.
Randall TD, Heath AW, Santos-Argumedo L, Howard MC, Weissman IL, Lund FE
Immunity 1998 Jun;8(6):733-42
Immunity 1998 Jun;8(6):733-42
A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas.
Stamenkovic I, Clark EA, Seed B
The EMBO journal 1989 May;8(5):1403-10
The EMBO journal 1989 May;8(5):1403-10
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