Antibody data
- Antibody Data
- Antigen structure
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- Product number
- abx004499 - Provider product page
- Provider
- Abbexa
- Product name
- X-Ray Repair Cross Complementing 5 (XRCC5) Antibody
- Antibody type
- Polyclonal
- Description
- XRCC5 Antibody is a Rabbit Polyclonal antibody against XRCC5. The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- > 1 mg/ml
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
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