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Protein structure
XRCC5
X-ray repair cross complementing 5KARP-1, KU80, Ku86, KUB2
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  MA5-12933 |
72 references | Monoclonal |
WB
ICC
IP
FC
OA
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| Proteintech Group | 16389-1-AP |
30 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| antibodies-online | ABIN969463 |
2 references | Monoclonal |
WB
EL
ICC
IHC
FC
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| LSBio | LS-C186112 |
Polyclonal |
WB
ICC
IP
IHC
|
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| GeneTex | GTX109935 |
4 references | Polyclonal |
WB
ICC
IP
IHC
|
|
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