FNab09555

antibody from FineTest Biotech
Targeting: XRCC5 KARP-1, KU80, Ku86, KUB2
Provider product page for FNab09555
Western blot
ELISA
Immunohistochemistry

Antibody data

Product number
FNab09555 - Provider product page
Provider
FineTest Biotech
Product name
XRCC5/Ku80 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
X-ray repair complementing defectiv
e repair in Chinese hamster cells 5
(double-strand-break rejoining)
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
XRCC5 protein structure - FNab09555 shown in red.