Ab112438

antibody from Aladdin Scientific Corporation
Targeting: XRCC5 KARP-1, KU80, Ku86, KUB2
Provider product page for Ab112438
Western blot
ELISA
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
Ab112438 - Provider product page
Provider
Aladdin Scientific Corporation
Product name
Ku80 Mouse mAb
Antibody type
Monoclonal
Description
Application: WB: 1/500 - 1/2000IHC: 1/200 - 1/1000IF/ICC: 1/200 - 1/1000Flow: 1/200 - 1/400ELISA: 1/10000The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Reactivity
Human, Mouse
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
corresponding to amino acids 61-340
of Human Ku80
Antibody clone number
5C5
Vial size
100μl,10μl,1ml,50μl
Concentration
1 mg/ml
Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid repeated freeze / thaw cycles.
XRCC5 protein structure - Ab112438 shown in red.