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Protein structure
PAFAH1B1
Platelet activating factor acetylhydrolase 1b regulatory subunit 1LIS1, MDCR, MDS, NudF, PAFAH
This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq, Apr 2009]
Top validated antibodies |
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| Novus Biologicals |  NBP1-03125 |
2 references | Polyclonal |
WB
EL
ICC
IHC
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| antibodies-online | ABIN2493017 |
Polyclonal |
WB
ICC
IHC
FC
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| Invitrogen Antibodies | PA5-20419 |
1 references | Polyclonal |
WB
ICC
OA
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| Proteintech Group | 20678-1-AP |
1 references | Polyclonal |
WB
EL
IHC
|
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| Abnova Corporation | H00005048-M03 |
Monoclonal |
WB
EL
ICC
|
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