Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- NB100-1475 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-1475, RRID:AB_2139442
- Product name
- Goat Polyclonal LRP-6 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. This antibody is expected to recognise an epitope corresponding to aa 1546-1560 of human LRP6 protein.
- Reactivity
- Human, Mouse
- Host
- Goat
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Interferon-gamma regulates intestinal epithelial homeostasis through converging beta-catenin signaling pathways.
Mutation in EGFP domain of LDL receptor-related protein 6 impairs cellular LDL clearance.
LDL-receptor-related proteins in Wnt signal transduction.
Nava P, Koch S, Laukoetter MG, Lee WY, Kolegraff K, Capaldo CT, Beeman N, Addis C, Gerner-Smidt K, Neumaier I, Skerra A, Li L, Parkos CA, Nusrat A
Immunity 2010 Mar 26;32(3):392-402
Immunity 2010 Mar 26;32(3):392-402
Mutation in EGFP domain of LDL receptor-related protein 6 impairs cellular LDL clearance.
Liu W, Mani S, Davis NR, Sarrafzadegan N, Kavathas PB, Mani A
Circulation research 2008 Nov 21;103(11):1280-8
Circulation research 2008 Nov 21;103(11):1280-8
LDL-receptor-related proteins in Wnt signal transduction.
Tamai K, Semenov M, Kato Y, Spokony R, Liu C, Katsuyama Y, Hess F, Saint-Jeannet JP, He X
Nature 2000 Sep 28;407(6803):530-5
Nature 2000 Sep 28;407(6803):530-5
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: LRP-6 Antibody [NB100-1475] - Analysis of paraffin embedded Human Kidney using this antibody at 4ug/ml. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.