APR05566G

antibody from Leading Biology
Targeting: TOP2B
Provider product page for APR05566G
Western blot

Antibody data

Product number
APR05566G - Provider product page
Provider
Leading Biology
Product name
Topoisomerase 2 beta Antibody
Antibody type
Polyclonal
Description
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Indirectly involved in vitamin D- coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR- mediated transrepression of the CYP27B1 gene.
Reactivity
Human
Host
Rabbit
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
TOP2B protein structure - APR05566G shown in red.