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Protein structure
DSG1
Desmoglein 1CDHF4, DSG
This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015]
Top validated antibodies |
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| Invitrogen Antibodies |  32-6000 |
19 references | Monoclonal |
WB
IP
IHC
OA
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| Proteintech Group | 24587-1-AP |
7 references | Polyclonal |
EL
ICC
IHC
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| NSJ Bioreagents | V3265 |
Monoclonal |
WB
ICC
FC
OA
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| Novus Biologicals | AF944 |
2 references | Polyclonal |
WB
IHC
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| OriGene | AM26377PU-N |
Monoclonal |
WB
ICC
IP
IHC
|
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