3294

antibody from Cell Signaling Technology, Inc

Targeting: ERN1 IRE1, IRE1P

Western blot (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Antibody Data

Product number

3294

Provider

Cell Signaling Technology, Inc

Proper citation

Cell Signaling Technology Cat#3294, RRID:AB_823545

Product name

IRE1α (14C10) Rabbit mAb

Antibody type

Monoclonal

Reactivity

Human, Mouse, Rat

Host

Rabbit

Storage

-20°C

References

Submitted references

The unfolded-protein-response sensor IRE-1α regulates the function of CD8α+ dendritic cells.

Osorio F, Tavernier SJ, Hoffmann E, Saeys Y, Martens L, Vetters J, Delrue I, De Rycke R, Parthoens E, Pouliot P, Iwawaki T, Janssens S, Lambrecht BN
Nature immunology 2014 Mar;15(3):248-57

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XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway.

Chen X, Iliopoulos D, Zhang Q, Tang Q, Greenblatt MB, Hatziapostolou M, Lim E, Tam WL, Ni M, Chen Y, Mai J, Shen H, Hu DZ, Adoro S, Hu B, Song M, Tan C, Landis MD, Ferrari M, Shin SJ, Brown M, Chang JC, Liu XS, Glimcher LH
Nature 2014 Apr 3;508(7494):103-7

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Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors.

De Raedt T, Walton Z, Yecies JL, Li D, Chen Y, Malone CF, Maertens O, Jeong SM, Bronson RT, Lebleu V, Kalluri R, Normant E, Haigis MC, Manning BD, Wong KK, Macleod KF, Cichowski K
Cancer cell 2011 Sep 13;20(3):400-13