Tissue expression
Cell line expression
Protein structure
ANGPT2
Angiopoietin 2Ang2
This gene belongs to the angiopoietin family of growth factors. The protein encoded by this gene is an antagonist of angiopoietin 1, and both angiopoietin 1 and angiopoietin 2 are ligands for the endothelial TEK receptor tyrosine kinase. Angiopoietin 2 is upregulated in multiple inflammatory diseases and is implicated in the direct control of inflammation-related signaling pathways. The encoded protein affects angiogenesis during embryogenesis and tumorigenesis, disrupts the vascular remodeling ability of angiopoietin 1, and may induce endothelial cell apoptosis. This gene serves a prognostic biomarker for acute respiratory distress syndrome. [provided by RefSeq, Aug 2020]
Top validated antibodies |
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Boster Biological Technology | ![]() |
9 references | Polyclonal |
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Proteintech Group | ![]() |
22 references | Polyclonal |
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NSJ Bioreagents | ![]() |
Polyclonal |
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antibodies-online | ![]() |
3 references | Polyclonal |
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GeneTex | ![]() |
1 references | Polyclonal |
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