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LearnAF2368
antibody from R&D Systems
Targeting: LRP1
A2MR, APOER, APR, CD91, IGFBP-3R, IGFBP3R1, LRP, LRP1A
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- AF2368 - Provider product page
- Provider
- R&D Systems
- Product name
- Human LRP-1 Cluster II Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human LRP-1 Cluster II in direct ELISAs and Western blots. In direct ELISAs, less than 2% cross-reactivity with recombinant human (rh) CRP-6 and rhMegalin-C4 is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
Q07954- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Low-Density Lipoprotein Receptor-Related Protein-1 Is a Therapeutic Target in Acute Myocardial Infarction.
Bovine lactoferrin inhibits Japanese encephalitis virus by binding to heparan sulfate and receptor for low density lipoprotein.
Toldo S, Austin D, Mauro AG, Mezzaroma E, Van Tassell BW, Marchetti C, Carbone S, Mogelsvang S, Gelber C, Abbate A
JACC. Basic to translational science 2017 Oct;2(5):561-574
JACC. Basic to translational science 2017 Oct;2(5):561-574
Bovine lactoferrin inhibits Japanese encephalitis virus by binding to heparan sulfate and receptor for low density lipoprotein.
Chien YJ, Chen WJ, Hsu WL, Chiou SS
Virology 2008 Sep 15;379(1):143-51
Virology 2008 Sep 15;379(1):143-51
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- LRP-1 Cluster II in HepG2 Human Cell Line. LRP-1 Cluster II was detected in immersion fixed HepG2 human hepatocellular carcinoma cell line using Goat Anti-Human LRP-1 Cluster II Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2368) at 3 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # NL001) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm and nuclei. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.
Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- LRP-1 Cluster II in Human Liver. LRP-1 Cluster II was detected in immersion fixed paraffin-embedded sections of human liver using Goat Anti-Human LRP-1 Cluster II Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2368) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC004). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell membranes and cytoplasm. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.
