METAP2

gene product
MAP2, MNPEP, p67
This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Knockdown Initiative

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated in Knockdown Initative
Eligible for validation in KDI
149 antibodies from 22 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeKDWBELICCIPIHCFC
Atlas Antibodies
1 antibody
Abnova Corporation
3 antibodies
OriGene
2 antibodies
NovoPro Bioscience Inc.
7 antibodies
antibodies-online
53 antibodies
LifeSpan BioSciences, Inc.
30 antibodies
Novus Biologicals
1 antibody
Proteintech Group
1 antibody
R&D Systems
1 antibody
Aviva Systems Biology
4 antibodies
Invitrogen Antibodies
3 antibodies
Acris Antibodies GmbH
4 antibodies
Biorbyt
5 antibodies
GeneTex
2 antibodies
Bethyl Laboratories, Inc.
3 antibodies
RabMAbs
4 antibodies
Sino Biological Inc.
1 antibody
Abgent
2 antibodies
MyBioSource
3 antibodies
Cell Signaling Technology, Inc
1 antibody
United States Biological
15 antibodies
Sigma-Aldrich
3 antibodies