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- Antibody Data
- Antigen structure
- References [11]
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- Validations
- Immunohistochemistry [1]
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- Product number
- 66198-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- INS antibody
- Antibody type
- Monoclonal
- Description
- INS antibody (Cat. #66198-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 4B6A7
- Vial size
- 20ul, 150ul
Submitted references Type IIB PKA is highly expressed in β cells and controls cell proliferation via regulating Cyclin D1 expression.
Mof acetyltransferase inhibition ameliorates glucose intolerance and islet dysfunction of type 2 diabetes via targeting pancreatic α-cells.
Amino acids-Rab1A-mTORC1 signaling controls whole-body glucose homeostasis.
Disrupted glucose homeostasis and skeletal-muscle-specific glucose uptake in an exocyst knockout mouse model.
Stomach secretes estrogen in response to the blood triglyceride levels.
Green light exposure aggravates high-fat diet feeding-induced hepatic steatosis and pancreatic dysfunction in male mice.
Novel Short-Clustered Maltodextrin as a Dietary Starch Substitute Attenuates Metabolic Dysregulation and Restructures Gut Microbiota in db/db Mice.
Involvement of Estrogen Receptor-α in the Activation of Nrf2-Antioxidative Signaling Pathways by Silibinin in Pancreatic β-Cells.
Mitomycin C treatment improves pancreatic islet graft longevity in intraportal islet transplantation by suppressing proinflammatory response.
Glutathione prevents chronic oscillating glucose intake-induced β-cell dedifferentiation and failure.
Chronic oscillating glucose challenges disarrange innate immune homeostasis to potentiate the variation of neutrophil-lymphocyte ratio in rats with or without hidden diabetes mellitus.
Jiang Y, Zhu L, Wu D, Ni Y, Huang C, Ye H, Yang Y, Liu R, Li Y
The FEBS journal 2021 Nov 28;
The FEBS journal 2021 Nov 28;
Mof acetyltransferase inhibition ameliorates glucose intolerance and islet dysfunction of type 2 diabetes via targeting pancreatic α-cells.
Guo X, Cui C, Song J, He Q, Zang N, Hu H, Wang X, Li D, Wang C, Hou X, Li X, Liang K, Yan F, Chen L
Molecular and cellular endocrinology 2021 Nov 1;537:111425
Molecular and cellular endocrinology 2021 Nov 1;537:111425
Amino acids-Rab1A-mTORC1 signaling controls whole-body glucose homeostasis.
Zhang X, Wang X, Yuan Z, Radford SJ, Liu C, Libutti SK, Zheng XFS
Cell reports 2021 Mar 16;34(11):108830
Cell reports 2021 Mar 16;34(11):108830
Disrupted glucose homeostasis and skeletal-muscle-specific glucose uptake in an exocyst knockout mouse model.
Fujimoto BA, Young M, Nakamura N, Ha H, Carter L, Pitts MW, Torres D, Noh HL, Suk S, Kim JK, Polgar N
The Journal of biological chemistry 2021 Jan-Jun;296:100482
The Journal of biological chemistry 2021 Jan-Jun;296:100482
Stomach secretes estrogen in response to the blood triglyceride levels.
Ito T, Yamamoto Y, Yamagishi N, Kanai Y
Communications biology 2021 Dec 7;4(1):1364
Communications biology 2021 Dec 7;4(1):1364
Green light exposure aggravates high-fat diet feeding-induced hepatic steatosis and pancreatic dysfunction in male mice.
Zhang S, Xu M, Shen Z, Shang C, Zhang W, Chen S, Liu C
Ecotoxicology and environmental safety 2021 Dec 1;225:112802
Ecotoxicology and environmental safety 2021 Dec 1;225:112802
Novel Short-Clustered Maltodextrin as a Dietary Starch Substitute Attenuates Metabolic Dysregulation and Restructures Gut Microbiota in db/db Mice.
Kong H, Yu L, Gu Z, Li C, Ban X, Cheng L, Hong Y, Li Z
Journal of agricultural and food chemistry 2020 Nov 4;68(44):12400-12412
Journal of agricultural and food chemistry 2020 Nov 4;68(44):12400-12412
Involvement of Estrogen Receptor-α in the Activation of Nrf2-Antioxidative Signaling Pathways by Silibinin in Pancreatic β-Cells.
Chu C, Gao X, Li X, Zhang X, Ma R, Jia Y, Li D, Wang D, Xu F
Biomolecules & therapeutics 2020 Mar 1;28(2):163-171
Biomolecules & therapeutics 2020 Mar 1;28(2):163-171
Mitomycin C treatment improves pancreatic islet graft longevity in intraportal islet transplantation by suppressing proinflammatory response.
Yamane K, Anazawa T, Tada S, Fujimoto N, Inoguchi K, Emoto N, Nagai K, Masui T, Okajima H, Takaori K, Sumi S, Uemoto S
Scientific reports 2020 Jul 21;10(1):12086
Scientific reports 2020 Jul 21;10(1):12086
Glutathione prevents chronic oscillating glucose intake-induced β-cell dedifferentiation and failure.
Zhang J, An H, Ni K, Chen B, Li H, Li Y, Sheng G, Zhou C, Xie M, Chen S, Zhou T, Yang G, Chen X, Wu G, Jin S, Li M
Cell death & disease 2019 Apr 11;10(4):321
Cell death & disease 2019 Apr 11;10(4):321
Chronic oscillating glucose challenges disarrange innate immune homeostasis to potentiate the variation of neutrophil-lymphocyte ratio in rats with or without hidden diabetes mellitus.
Yang G, Yan R, Tong H, Zhang J, Chen B, Xue X, Wang J, Chu M, Jin S, Li M
Diabetes, metabolic syndrome and obesity : targets and therapy 2018;11:277-288
Diabetes, metabolic syndrome and obesity : targets and therapy 2018;11:277-288
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Insulin antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human Insulin. This antibody recognizes human, mouse antigen. The Insulin antibody has been validated for the following applications: ELISA, IHC analysis.
