INS

gene product
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
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895 antibodies from 20 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
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R&D Systems
8 antibodies
Novus Biologicals
81 antibodies
antibodies-online
373 antibodies
Acris Antibodies GmbH
40 antibodies
Abnova Corporation
30 antibodies
Cell Signaling Technology, Inc
5 antibodies
Creative Biomart
128 antibodies
Thermo Fisher Scientific Pierce
34 antibodies
LifeSpan BioSciences, Inc.
82 antibodies
Aviva Systems Biology
34 antibodies
United States Biological
8 antibodies
Proteintech Group
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
Enzo Life Sciences
5 antibodies
RabMAbs
4 antibodies
Boster Immunoleader Biotechnology
1 antibody
RayBiotech, Inc.
14 antibodies
Abbiotec
3 antibodies
EMD Millipore
4 antibodies