INS

gene product
IDDM1, IDDM2
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
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1153 antibodies from 26 providers.

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AntibodyRefsTypeKDWBELICCIPIHCFC
Novus Biologicals
159 antibodies
GeneTex
31 antibodies
R&D Systems
8 antibodies
Abgent
6 antibodies
antibodies-online
440 antibodies
Acris Antibodies GmbH
50 antibodies
BosterBio
1 antibody
Abnova Corporation
29 antibodies
Thermo Fisher Scientific Pierce
34 antibodies
Enzo Life Sciences
5 antibodies
Cell Signaling Technology, Inc
8 antibodies
Biorbyt
76 antibodies