Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [2]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- AP02344PU-S - Provider product page
- Provider
- Acris Antibodies GmbH
- Proper citation
- Acris Antibodies GmbH Cat#AP02344PU-S, RRID:AB_1623175
- Product name
- anti STAT3 pTyr705
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of Ttyrosine 705 (A-P-Y(p)-L-K) derived from Human STAT3.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 50 µl
- Concentration
- 1.0 mg/ml
Submitted references Osteopontin shapes immunosuppression in the metastatic niche.
PF-04691502 triggers cell cycle arrest, apoptosis and inhibits the angiogenesis in hepatocellular carcinoma cells.
Atrial natriuretic peptide suppresses Th17 development through regulation of cGMP-dependent protein kinase and PI3K-Akt signaling pathways.
Resistance to bleomycin-induced lung fibrosis in MMP-8 deficient mice is mediated by interleukin-10.
Significance and relationship between Cripto-1 and p-STAT3 expression in gastric cancer and precancerous lesions.
Overexpression of LEDGF/DFS70 induces IL-6 via p38 activation in HaCaT cells, similar to that seen in the psoriatic condition.
Low-level bisphenol A increases production of glial fibrillary acidic protein in differentiating astrocyte progenitor cells through excessive STAT3 and Smad1 activation.
Sangaletti S, Tripodo C, Sandri S, Torselli I, Vitali C, Ratti C, Botti L, Burocchi A, Porcasi R, Tomirotti A, Colombo MP, Chiodoni C
Cancer research 2014 Sep 1;74(17):4706-19
Cancer research 2014 Sep 1;74(17):4706-19
PF-04691502 triggers cell cycle arrest, apoptosis and inhibits the angiogenesis in hepatocellular carcinoma cells.
Wang FZ, Peng-Jiao, Yang NN, Chuang-Yuan, Zhao YL, Liu QQ, Fei HR, Zhang JG
Toxicology letters 2013 Jul 4;220(2):150-6
Toxicology letters 2013 Jul 4;220(2):150-6
Atrial natriuretic peptide suppresses Th17 development through regulation of cGMP-dependent protein kinase and PI3K-Akt signaling pathways.
Ma L, Li J, Wang G, Gong S, Zhang L, Li K, Ji X, Liu Y, Chen P, Xiang X
Regulatory peptides 2013 Feb 10;181:9-16
Regulatory peptides 2013 Feb 10;181:9-16
Resistance to bleomycin-induced lung fibrosis in MMP-8 deficient mice is mediated by interleukin-10.
García-Prieto E, González-López A, Cabrera S, Astudillo A, Gutiérrez-Fernández A, Fanjul-Fernandez M, Batalla-Solís E, Puente XS, Fueyo A, López-Otín C, Albaiceta GM
PloS one 2010 Oct 7;5(10):e13242
PloS one 2010 Oct 7;5(10):e13242
Significance and relationship between Cripto-1 and p-STAT3 expression in gastric cancer and precancerous lesions.
Zhang JG, Zhao J, Xin Y
World journal of gastroenterology : WJG 2010 Feb 7;16(5):571-7
World journal of gastroenterology : WJG 2010 Feb 7;16(5):571-7
Overexpression of LEDGF/DFS70 induces IL-6 via p38 activation in HaCaT cells, similar to that seen in the psoriatic condition.
Takeichi T, Sugiura K, Muro Y, Matsumoto K, Ogawa Y, Futamura K, Kaminuma O, Hashimoto N, Shimoyama Y, Saito H, Tomita Y
The Journal of investigative dermatology 2010 Dec;130(12):2760-7
The Journal of investigative dermatology 2010 Dec;130(12):2760-7
Low-level bisphenol A increases production of glial fibrillary acidic protein in differentiating astrocyte progenitor cells through excessive STAT3 and Smad1 activation.
Yamaguchi H, Zhu J, Yu T, Sasaki K, Umetsu H, Kidachi Y, Ryoyama K
Toxicology 2006 Sep 21;226(2-3):131-42
Toxicology 2006 Sep 21;226(2-3):131-42
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Supportive validation
- Submitted by
- Acris Antibodies GmbH (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from HeLa cells using STAT3 (phospho-Tyr705) Antibody Cat.-No AP02344PU
- Submitted by
- Acris Antibodies GmbH (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from Hela cells untreated or treated with IFN a using STAT3 (Phospho-Tyr705) Antibody Cat.-No AP02344PU
Supportive validation
- Submitted by
- Acris Antibodies GmbH (provider)
- Main image
- Experimental details
- Immunofluorescence staining of methanol-fixed MEF cells untreated or treated with IFN using STAT3 (Phospho-Tyr705) Antibody Cat.-No AP02344PUÂ
Supportive validation
- Submitted by
- Acris Antibodies GmbH (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT3 (phospho-Tyr705) Antibody Cat.-No AP02344PU
- Submitted by
- Acris Antibodies GmbH (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human Lung carcinoma tissue using STAT3 (Phospho-Tyr705) Antibody Cat.-No AP02344PU