STAT3

gene product
APRF
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
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798 antibodies from 31 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Cell Signaling Technology, Inc
19 antibodies
Atlas Antibodies
3 antibodies
Abnova Corporation
24 antibodies
Proteintech Group
3 antibodies
antibodies-online
282 antibodies
Novus Biologicals
42 antibodies
R&D Systems
10 antibodies
Thermo Fisher Scientific Pierce
15 antibodies
GeneTex
29 antibodies
Aviva Systems Biology
23 antibodies
Acris Antibodies GmbH
40 antibodies
Signalway Antibody LLC
5 antibodies
LifeSpan BioSciences, Inc.
130 antibodies
SignalChem
5 antibodies
Boster Immunoleader Biotechnology
2 antibodies
Bethyl Laboratories, Inc.
2 antibodies
OriGene
1 antibody
Everest Biotech
2 antibodies
RabMAbs
14 antibodies
Creative Biomart
50 antibodies
Enzo Life Sciences
9 antibodies
GenWay
12 antibodies
EMD Millipore
9 antibodies
BioLegend
4 antibodies
Spring Bioscience
4 antibodies
Abbiotec
3 antibodies
United States Biological
37 antibodies
RayBiotech, Inc.
6 antibodies
Sigma-Aldrich
9 antibodies
Rockland Immunochemicals, Inc.
2 antibodies
Active Motif
2 antibodies