STAT3

gene product
APRF
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
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869 antibodies from 36 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Cell Signaling Technology, Inc
21 antibodies
Proteintech Group
3 antibodies
Abnova Corporation
25 antibodies
Novus Biologicals
41 antibodies
Atlas Antibodies
3 antibodies
antibodies-online
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R&D Systems
10 antibodies
Bioworld Technology, Inc
9 antibodies
Thermo Fisher Scientific Pierce
15 antibodies
Aviva Systems Biology
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GeneTex
29 antibodies
Biorbyt
22 antibodies
Acris Antibodies GmbH
40 antibodies
Abgent
16 antibodies
Signalway Antibody LLC
5 antibodies
LifeSpan BioSciences, Inc.
147 antibodies
SignalChem
5 antibodies
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2 antibodies
Bethyl Laboratories, Inc.
2 antibodies
OriGene
1 antibody
Everest Biotech
2 antibodies
RabMAbs
14 antibodies
Creative Biomart
51 antibodies
Enzo Life Sciences
9 antibodies
BioLegend
4 antibodies
GenWay
12 antibodies
Bioss
3 antibodies
EMD Millipore
9 antibodies
Spring Bioscience
4 antibodies
Abbiotec
3 antibodies
United States Biological
37 antibodies
RayBiotech, Inc.
6 antibodies
Sigma-Aldrich
9 antibodies
Rockland Immunochemicals, Inc.
2 antibodies
Active Motif
2 antibodies
Exalpha Biologicals, Inc.
1 antibody