STAT6

gene product
D12S1644, IL-4-STAT
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
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562 antibodies from 28 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Bethyl Laboratories, Inc.
2 antibodies
Novus Biologicals
46 antibodies
Cell Signaling Technology, Inc
6 antibodies
antibodies-online
211 antibodies
GeneTex
22 antibodies
Abnova Corporation
19 antibodies
Proteintech Group
2 antibodies
R&D Systems
9 antibodies
Signalway Antibody LLC
4 antibodies
LifeSpan BioSciences, Inc.
76 antibodies
Atlas Antibodies
1 antibody
Aviva Systems Biology
15 antibodies
Acris Antibodies GmbH
23 antibodies
Thermo Fisher Scientific Pierce
9 antibodies
Boster Immunoleader Biotechnology
2 antibodies
RabMAbs
5 antibodies
Creative Biomart
57 antibodies
Rockland Immunochemicals, Inc.
2 antibodies
BioLegend
1 antibody
Bioworld Technology, Inc
4 antibodies
Spring Bioscience
4 antibodies
GenWay
14 antibodies
United States Biological
9 antibodies
EMD Millipore
5 antibodies
Sigma-Aldrich
8 antibodies
Abbiotec
2 antibodies
Abiocode, Inc.
1 antibody
RayBiotech, Inc.
3 antibodies