ABIN967101

antibody from antibodies-online

Targeting: STAT6 D12S1644, IL-4-STAT

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN967101

Provider

antibodies-online

Product name

anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (pTyr641) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human STAT6 around the phosphorylation site of Tyrosine 641 (R-G-YP-V-P).

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human

Host

Rabbit

Epitope

pTyr641

Vial size

100 μg

Concentration

100ug/100ul.

Storage

-20°C

References

Submitted references

The IL-4 receptor: signaling mechanisms and biologic functions.

Nelms K, Keegan AD, Zamorano J, Ryan JJ, Paul WE
Annual review of immunology 1999;17:701-38

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Interleukin-13 is a potent activator of JAK3 and STAT6 in cells expressing interleukin-2 receptor-gamma and interleukin-4 receptor-alpha.

Malabarba MG, Rui H, Deutsch HH, Chung J, Kalthoff FS, Farrar WL, Kirken RA
The Biochemical journal 1996 Nov 1;319 ( Pt 3):865-72

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Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis.

Quelle FW, Shimoda K, Thierfelder W, Fischer C, Kim A, Ruben SM, Cleveland JL, Pierce JH, Keegan AD, Nelms K
Molecular and cellular biology 1995 Jun;15(6):3336-43

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An interleukin-4-induced transcription factor: IL-4 Stat.

Hou J, Schindler U, Henzel WJ, Ho TC, Brasseur M, McKnight SL
Science (New York, N.Y.) 1994 Sep 16;265(5179):1701-6