TAP2

gene product
ABCB3, D6S217E, PSF2, RING11
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Feb 2014]
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58 antibodies from 15 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
4 antibodies
Acris Antibodies GmbH
2 antibodies
Atlas Antibodies
1 antibody
antibodies-online
25 antibodies
LifeSpan BioSciences, Inc.
12 antibodies
Abnova Corporation
2 antibodies
Cell Signaling Technology, Inc
1 antibody
GenWay
2 antibodies
Creative Biomart
3 antibodies
Bioworld Technology, Inc
1 antibody
RayBiotech, Inc.
1 antibody
Sigma-Aldrich
1 antibody
Biorbyt
1 antibody
Boster Immunoleader Biotechnology
1 antibody
GeneTex
1 antibody