ZAP70

gene product
SRK, STD, ZAP-70
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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993 antibodies from 30 providers.

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AntibodyRefsTypeKDWBELICCIPIHCFC
Cell Signaling Technology, Inc
11 antibodies
antibodies-online
381 antibodies
Proteintech Group
4 antibodies
Novus Biologicals
34 antibodies
Signalway Antibody LLC
4 antibodies
GeneTex
29 antibodies
Abgent
9 antibodies
Bioworld Technology, Inc
8 antibodies
Acris Antibodies GmbH
44 antibodies
Aviva Systems Biology
26 antibodies
Biorbyt
25 antibodies
Thermo Fisher Scientific Pierce
16 antibodies
R&D Systems
4 antibodies
Bethyl Laboratories, Inc.
9 antibodies
Abnova Corporation
21 antibodies
Atlas Antibodies
1 antibody
LifeSpan BioSciences, Inc.
117 antibodies
RabMAbs
14 antibodies
Spring Bioscience
4 antibodies
Creative Biomart
90 antibodies