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Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Product number
- ABIN967585 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (pTyr493) antibody
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Purified from tissue culture supernatant or ascites by affinity chromatography.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Epitope
- pTyr493
- Isotype
- IgG
- Antibody clone number
- 1a
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- 4°C
Submitted references Mutation of tyrosines 492/493 in the kinase domain of ZAP-70 affects multiple T-cell receptor signaling pathways.
Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function.
ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency.
Mège D, Di Bartolo V, Germain V, Tuosto L, Michel F, Acuto O
The Journal of biological chemistry 1996 Dec 20;271(51):32644-52
The Journal of biological chemistry 1996 Dec 20;271(51):32644-52
Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function.
Chan AC, Dalton M, Johnson R, Kong GH, Wang T, Thoma R, Kurosaki T
The EMBO journal 1995 Jun 1;14(11):2499-508
The EMBO journal 1995 Jun 1;14(11):2499-508
ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency.
Chan AC, Kadlecek TA, Elder ME, Filipovich AH, Kuo WL, Iwashima M, Parslow TG, Weiss A
Science (New York, N.Y.) 1994 Jun 10;264(5165):1599-601
Science (New York, N.Y.) 1994 Jun 10;264(5165):1599-601
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