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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Product number
- ABIN197085 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1) (pTyr349) antibody
- Antibody type
- Polyclonal
- Description
- Affinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- pTyr349
- Vial size
- 50 μL
- Storage
- Store the antibody (in aliquots) at -20°C.
- Handling
- Avoid repeated freezing and thawing.
Submitted references ShcA mediates the dominant pathway to extracellular signal-regulated kinase activation during early thymic development.
Cooperation and selectivity of the two Grb2 binding sites of p52Shc in T-cell antigen receptor signaling to Ras family GTPases and Myc-dependent survival.
The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein-protein interactions.
Trampont P, Zhang L, Ravichandran KS
Molecular and cellular biology 2006 Dec;26(23):9035-44
Molecular and cellular biology 2006 Dec;26(23):9035-44
Cooperation and selectivity of the two Grb2 binding sites of p52Shc in T-cell antigen receptor signaling to Ras family GTPases and Myc-dependent survival.
Patrussi L, Savino MT, Pellegrini M, Paccani SR, Migliaccio E, Plyte S, Lanfrancone L, Pelicci PG, Baldari CT
Oncogene 2005 Mar 24;24(13):2218-28
Oncogene 2005 Mar 24;24(13):2218-28
The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein-protein interactions.
van der Geer P, Wiley S, Gish GD, Pawson T
Current biology : CB 1996 Nov 1;6(11):1435-44
Current biology : CB 1996 Nov 1;6(11):1435-44
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