Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN968228 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1) (AA 359-473) antibody
- Antibody type
- Monoclonal
- Antigen
- Human SHC
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 30
- Vial size
- 50 µg
- Concentration
- 250 µg/ml
- Storage
- Store undiluted at -20° C.
Submitted references RACK1 is an insulin-like growth factor 1 (IGF-1) receptor-interacting protein that can regulate IGF-1-mediated Akt activation and protection from cell death.
Protein phosphatase 2A forms a molecular complex with Shc and regulates Shc tyrosine phosphorylation and downstream mitogenic signaling.
Intracellular signaling mechanisms leading to synergistic effects of endothelin-1 and stem cell factor on proliferation of cultured human melanocytes. Cross-talk via trans-activation of the tyrosine kinase c-kit receptor.
Integrin activation and focal complex formation in cardiac hypertrophy.
A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction.
Kiely PA, Sant A, O'Connor R
The Journal of biological chemistry 2002 Jun 21;277(25):22581-9
The Journal of biological chemistry 2002 Jun 21;277(25):22581-9
Protein phosphatase 2A forms a molecular complex with Shc and regulates Shc tyrosine phosphorylation and downstream mitogenic signaling.
Ugi S, Imamura T, Ricketts W, Olefsky JM
Molecular and cellular biology 2002 Apr;22(7):2375-87
Molecular and cellular biology 2002 Apr;22(7):2375-87
Intracellular signaling mechanisms leading to synergistic effects of endothelin-1 and stem cell factor on proliferation of cultured human melanocytes. Cross-talk via trans-activation of the tyrosine kinase c-kit receptor.
Imokawa G, Kobayasi T, Miyagishi M
The Journal of biological chemistry 2000 Oct 27;275(43):33321-8
The Journal of biological chemistry 2000 Oct 27;275(43):33321-8
Integrin activation and focal complex formation in cardiac hypertrophy.
Laser M, Willey CD, Jiang W, Cooper G 4th, Menick DR, Zile MR, Kuppuswamy D
The Journal of biological chemistry 2000 Nov 10;275(45):35624-30
The Journal of biological chemistry 2000 Nov 10;275(45):35624-30
A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction.
Pelicci G, Lanfrancone L, Grignani F, McGlade J, Cavallo F, Forni G, Nicoletti I, Grignani F, Pawson T, Pelicci PG
Cell 1992 Jul 10;70(1):93-104
Cell 1992 Jul 10;70(1):93-104
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