Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
ACACA
Acetyl-CoA carboxylase alphaACAC, ACC, ACC1
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
| Proteintech Group |  21923-1-AP |
69 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
|
|
| Invitrogen Antibodies | PA5-17564 |
4 references | Polyclonal |
WB
ICC
IP
IHC
FC
OA
|
|
| GeneTex | GTX132081 |
2 references | Polyclonal |
WB
ICC
IHC
|
|
| NovoPro Bioscience Inc. | 107732 |
Polyclonal |
WB
EL
ICC
IP
IHC
|
||
| antibodies-online | ABIN393873 |
5 references | Monoclonal |
WB
EL
|
|
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider