Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- NBP2-34642B - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal ErbB2/Her2 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A purified. Recognizes a protein of 185kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This MAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Biotin
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C in the dark.
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Flow Cytometry: ErbB2/Her2 Antibody (HRB2/282) [Biotin] [NBP2-34642B] - A surface stain was performed on MCF7 Cells with ErbB2/Her2 Antibody (HRB2/282) NBP2-34642B and a matched isotype control. Both antibodies were conjugated to biotin. Cells were incubated in an antibody dilution of 2.5 ug/mL for 20 minutes at room temperature, followed by Streptavidin - R-Phycoerythrin Protein (2012-1000, Novus Biologicals).