PAB5391

antibody from Abnova Corporation

Targeting: ERBB2 CD340, HER-2, HER2, NEU, NGL

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB5391

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB5391, RRID:AB_1574743

Product name

ERBB2 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of ERBB2.

Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

More about: prognostic importance of low c-erbB2 expression in breast tumors.

Dittadi R, Gion M
Journal of the National Cancer Institute 2000 Sep 6;92(17):1443-4

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Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2.

Klapper LN, Waterman H, Sela M, Yarden Y
Cancer research 2000 Jul 1;60(13):3384-8

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Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers.

Muthuswamy SK, Gilman M, Brugge JS
Molecular and cellular biology 1999 Oct;19(10):6845-57

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of extracts from MDA-MB-231 cells using ERBB2 polyclonal antibody (Cat # PAB5391) .

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ERBB2 polyclonal antibody (Cat # PAB5391) .

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)