Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB5391 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB5391, RRID:AB_1574743
- Product name
- ERBB2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of ERBB2.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references More about: prognostic importance of low c-erbB2 expression in breast tumors.
Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2.
Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers.
Dittadi R, Gion M
Journal of the National Cancer Institute 2000 Sep 6;92(17):1443-4
Journal of the National Cancer Institute 2000 Sep 6;92(17):1443-4
Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2.
Klapper LN, Waterman H, Sela M, Yarden Y
Cancer research 2000 Jul 1;60(13):3384-8
Cancer research 2000 Jul 1;60(13):3384-8
Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers.
Muthuswamy SK, Gilman M, Brugge JS
Molecular and cellular biology 1999 Oct;19(10):6845-57
Molecular and cellular biology 1999 Oct;19(10):6845-57
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from MDA-MB-231 cells using ERBB2 polyclonal antibody (Cat # PAB5391) .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ERBB2 polyclonal antibody (Cat # PAB5391) .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)