Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362616 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (AA 875-879) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around AA 875-879 (T-E-Y-H-A) derived from Human HER2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- AA 875-879
- Isotype
- IgG
- Vial size
- 100 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references More about: prognostic importance of low c-erbB2 expression in breast tumors.
Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2.
Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers.
Activation of ErbB2 during wallerian degeneration of sciatic nerve.
Heterodimerization of epidermal growth factor receptor and wild-type or kinase-deficient Neu: a mechanism of interreceptor kinase activation and transphosphorylation.
Dittadi R, Gion M
Journal of the National Cancer Institute 2000 Sep 6;92(17):1443-4
Journal of the National Cancer Institute 2000 Sep 6;92(17):1443-4
Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2.
Klapper LN, Waterman H, Sela M, Yarden Y
Cancer research 2000 Jul 1;60(13):3384-8
Cancer research 2000 Jul 1;60(13):3384-8
Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers.
Muthuswamy SK, Gilman M, Brugge JS
Molecular and cellular biology 1999 Oct;19(10):6845-57
Molecular and cellular biology 1999 Oct;19(10):6845-57
Activation of ErbB2 during wallerian degeneration of sciatic nerve.
Kwon YK, Bhattacharyya A, Alberta JA, Giannobile WV, Cheon K, Stiles CD, Pomeroy SL
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997 Nov 1;17(21):8293-9
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997 Nov 1;17(21):8293-9
Heterodimerization of epidermal growth factor receptor and wild-type or kinase-deficient Neu: a mechanism of interreceptor kinase activation and transphosphorylation.
Qian X, LeVea CM, Freeman JK, Dougall WC, Greene MI
Proceedings of the National Academy of Sciences of the United States of America 1994 Feb 15;91(4):1500-4
Proceedings of the National Academy of Sciences of the United States of America 1994 Feb 15;91(4):1500-4
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