Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362619 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (AA 1246-1250) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around AA 1246-1250 (P-E-Y-L-G) derived from Human HER2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- AA 1246-1250
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Loss of fatty acid synthase inhibits the "HER2-PI3K/Akt axis" activity and malignant phenotype of Caco-2 cells.
The "HER2-PI3K/Akt-FASN Axis" regulated malignant phenotype of colorectal cancer cells.
Muc4/sialomucin complex, the intramembrane ErbB2 ligand, translocates ErbB2 to the apical surface in polarized epithelial cells.
Muc4/sialomucin complex, the intramembrane ErbB2 ligand, induces specific phosphorylation of ErbB2 and enhances expression of p27(kip), but does not activate mitogen-activated kinase or protein kinaseB/Akt pathways.
ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent manner.
Prognostic and predictive significance of ErbB-2 breast tumor levels measured by enzyme immunoassay.
Li N, Lu H, Chen C, Bu X, Huang P
Lipids in health and disease 2013 Jun 1;12:83
Lipids in health and disease 2013 Jun 1;12:83
The "HER2-PI3K/Akt-FASN Axis" regulated malignant phenotype of colorectal cancer cells.
Li N, Bu X, Wu P, Wu P, Huang P
Lipids 2012 Apr;47(4):403-11
Lipids 2012 Apr;47(4):403-11
Muc4/sialomucin complex, the intramembrane ErbB2 ligand, translocates ErbB2 to the apical surface in polarized epithelial cells.
Ramsauer VP, Carraway CA, Salas PJ, Carraway KL
The Journal of biological chemistry 2003 Aug 8;278(32):30142-7
The Journal of biological chemistry 2003 Aug 8;278(32):30142-7
Muc4/sialomucin complex, the intramembrane ErbB2 ligand, induces specific phosphorylation of ErbB2 and enhances expression of p27(kip), but does not activate mitogen-activated kinase or protein kinaseB/Akt pathways.
Jepson S, Komatsu M, Haq B, Arango ME, Huang D, Carraway CA, Carraway KL
Oncogene 2002 Oct 24;21(49):7524-32
Oncogene 2002 Oct 24;21(49):7524-32
ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent manner.
Ren Z, Schaefer TS
The Journal of biological chemistry 2002 Oct 11;277(41):38486-93
The Journal of biological chemistry 2002 Oct 11;277(41):38486-93
Prognostic and predictive significance of ErbB-2 breast tumor levels measured by enzyme immunoassay.
Eppenberger-Castori S, Kueng W, Benz C, Caduff R, Varga Z, Bannwart F, Fink D, Dieterich H, Hohl M, Müller H, Paris K, Schoumacher F, Eppenberger U
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001 Feb 1;19(3):645-56
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001 Feb 1;19(3):645-56
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