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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Product number
- ABIN108474 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) antibody
- Antibody type
- Monoclonal
- Antigen
- Other
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 2D4
- Vial size
- 0.1 mg
- Storage
- 4°C
Submitted references Herstatin inhibits heregulin-mediated breast cancer cell growth and overcomes tamoxifen resistance in breast cancer cells that overexpress HER-2.
Expression of herstatin, an autoinhibitor of HER-2/neu, inhibits transactivation of HER-3 by HER-2 and blocks EGF activation of the EGF receptor.
The HER-2/neu receptor tyrosine kinase gene encodes a secreted autoinhibitor.
Jhabvala-Romero F, Evans A, Guo S, Denton M, Clinton GM
Oncogene 2003 Nov 6;22(50):8178-86
Oncogene 2003 Nov 6;22(50):8178-86
Expression of herstatin, an autoinhibitor of HER-2/neu, inhibits transactivation of HER-3 by HER-2 and blocks EGF activation of the EGF receptor.
Azios NG, Romero FJ, Denton MC, Doherty JK, Clinton GM
Oncogene 2001 Aug 23;20(37):5199-209
Oncogene 2001 Aug 23;20(37):5199-209
The HER-2/neu receptor tyrosine kinase gene encodes a secreted autoinhibitor.
Doherty JK, Bond C, Jardim A, Adelman JP, Clinton GM
Proceedings of the National Academy of Sciences of the United States of America 1999 Sep 14;96(19):10869-74
Proceedings of the National Academy of Sciences of the United States of America 1999 Sep 14;96(19):10869-74
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