FNab03834

antibody from FineTest Biotech

Targeting: ERBB2 CD340, HER-2, HER2, NEU, NGL

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Immunocytochemistry

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Validation data

Product number: FNab03834 - Provider product page
Provider: FineTest Biotech
Product name: HER2/ErbB2 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: v-erb-b2 erythroblastic leukemia vi ral oncogene homolog 2, neuro/gliob lastoma derived oncogene homolog(av ian)
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

ERBB2 protein structure - FNab03834 shown in red.