ABIN966276

antibody from antibodies-online

Targeting: ERBB2 CD340, HER-2, HER2, NEU, NGL

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN966276

Provider

antibodies-online

Product name

anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (pTyr877) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human HER2 around the phosphorylation site of tyrosine 877 (T-E-YP-H-A).

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pTyr877

Vial size

100 μg

Concentration

100ug/100ul.

Storage

-20°C

References

Submitted references

More about: prognostic importance of low c-erbB2 expression in breast tumors.

Dittadi R, Gion M
Journal of the National Cancer Institute 2000 Sep 6;92(17):1443-4

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Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers.

Muthuswamy SK, Gilman M, Brugge JS
Molecular and cellular biology 1999 Oct;19(10):6845-57

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Heterodimerization of epidermal growth factor receptor and wild-type or kinase-deficient Neu: a mechanism of interreceptor kinase activation and transphosphorylation.

Qian X, LeVea CM, Freeman JK, Dougall WC, Greene MI
Proceedings of the National Academy of Sciences of the United States of America 1994 Feb 15;91(4):1500-4