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Protein structure
DCN
DecorinDSPG2, SLRR1B
This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. [provided by RefSeq, Nov 2015]
Top validated antibodies |
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| Atlas Antibodies |  HPA003315 |
4 references | Polyclonal |
WB
IHC
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| Proteintech Group | 14667-1-AP |
15 references | Polyclonal |
WB
EL
ICC
IHC
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| GeneTex | GTX101250 |
4 references | Polyclonal |
WB
ICC
IP
IHC
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| Invitrogen Antibodies | PA5-13538 |
2 references | Polyclonal |
WB
IHC
FC
OA
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| antibodies-online | ABIN1724881 |
2 references | Monoclonal |
WB
EL
FC
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