Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 508208 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#508208, RRID:AB_604135
- Product name
- Alexa Fluor® 647 anti-human IL-1â [JK1B-1]
- Antibody type
- Monoclonal
- Antigen
- Recombinant human IL-1 beta
- Description
- IL-1 refers to two proteins, IL-1α and IL-1β which are the products of distinct genes, but which are recognized by the same cell surface receptors. IL-1β is a potent immuno-modulator which mediates a wide range of immune and inflammatory responses including the activation of B and T cells. The JK1B-1 antibody reacts with human interleukin-1β (IL-1β) and baboon IL-1β. The JK1B-1 antibody does not recognize mouse IL-1β or human IL-1α or other cytokines. The JK1B-1 antibody can neutralize the bioactivity of natural or recombinant IL-1β.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Red dye
- Isotype
- IgG
- Vial size
- 100 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- LPS-stimulated (6 hour) human peripheral blood monocytes surface stained with CD14 PE, then intracellualar stained with JK1B-1 Alexa Fluorï¢ 647
- Conjugate
- Red dye