IL1B

gene product
IL-1B, IL1-BETA, IL1F2
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
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836 antibodies from 29 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Thermo Fisher Scientific Pierce
5 antibodies
R&D Systems
11 antibodies
Novus Biologicals
152 antibodies
Abnova Corporation
23 antibodies
antibodies-online
254 antibodies
Biorbyt
20 antibodies
Acris Antibodies GmbH
39 antibodies
Aviva Systems Biology
10 antibodies
Proteintech Group
2 antibodies
LifeSpan BioSciences, Inc.
89 antibodies
Abgent
6 antibodies
Abbiotec
1 antibody
GeneTex
21 antibodies
Cell Signaling Technology, Inc
6 antibodies
Creative Biomart
99 antibodies
Rockland Immunochemicals, Inc.
5 antibodies
GenWay
16 antibodies
Signalway Antibody LLC
1 antibody
BioLegend
18 antibodies
Boster Immunoleader Biotechnology
2 antibodies
RabMAbs
5 antibodies
EMD Millipore
6 antibodies
Sigma-Aldrich
5 antibodies
RayBiotech, Inc.
2 antibodies
Exalpha Biologicals, Inc.
4 antibodies
Bioworld Technology, Inc
1 antibody
eBioscience, An Affymetrix Company
13 antibodies
United States Biological
10 antibodies
Sino Biological Inc.
10 antibodies