IL1B

gene product
IL-1B, IL1-BETA, IL1F2
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
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890 antibodies from 33 providers.

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AntibodyRefsTypeKDWBELICCIPIHCFC
Novus Biologicals
174 antibodies
Thermo Fisher Scientific Pierce
8 antibodies
R&D Systems
11 antibodies
Abnova Corporation
23 antibodies
antibodies-online
316 antibodies
GeneTex
24 antibodies
Acris Antibodies GmbH
45 antibodies
Abgent
6 antibodies
Biorbyt
36 antibodies
OriGene
9 antibodies
Aviva Systems Biology
10 antibodies
LifeSpan BioSciences, Inc.
86 antibodies
Proteintech Group
2 antibodies
Abbiotec
1 antibody
Cell Signaling Technology, Inc
5 antibodies
Bioworld Technology, Inc
2 antibodies
Rockland Immunochemicals, Inc.
5 antibodies
GenWay
16 antibodies
Signalway Antibody LLC
1 antibody
BioLegend
19 antibodies
BosterBio
2 antibodies
Creative Diagnostics
15 antibodies