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- Antibody Data
- Antigen structure
- References [28]
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- Product number
- MAB601 - Provider product page
- Provider
- R&D Systems
- Product name
- Anti-Human IL-1 beta/IL-1F2 Monoclonal Antibody (Clone 2805)
- Antibody type
- Monoclonal
- Antigen
- E. coli-derived recombinant human IL-1β/IL-1F2
- Description
- Protein A or G purified from hybridoma culture supernatant
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 500 µg
Submitted references Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis.
Targeting the miR-665-3p-ATG4B-autophagy axis relieves inflammation and apoptosis in intestinal ischemia/reperfusion.
Exposure to wild-type AAV drives distinct capsid immunity profiles in humans.
DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia.
Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in Macrophages.
Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airways.
Zinc inhibits high glucose-induced NLRP3 inflammasome activation in human peritoneal mesothelial cells.
Vitamin D regulates cytokine patterns secreted by dendritic cells to promote differentiation of IL-22-producing T cells.
Alpha 1-antitrypsin does not inhibit human monocyte caspase-1.
Inflammasome priming by lipopolysaccharide is dependent upon ERK signaling and proteasome function.
Measurement of interleukin-33 (IL-33) and IL-33 receptors (sST2 and ST2L) in patients with rheumatoid arthritis.
IL-17C regulates the innate immune function of epithelial cells in an autocrine manner.
Resistance of human alveolar macrophages to Bacillus anthracis lethal toxin.
Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine.
Bacterial vaginosis, not HIV, is primarily responsible for increased vaginal concentrations of proinflammatory cytokines.
Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo.
Endogenous IL-32 controls cytokine and HIV-1 production.
Endogenous IL-32 controls cytokine and HIV-1 production.
Effect of serum content and diluent selection on assay sensitivity and signal intensity in multiplex bead-based immunoassays.
Ultrasensitive flow-based immunoassays using single-molecule counting.
Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1.
HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1.
Clinical outcome following acute ischaemic stroke relates to both activation and autoregulatory inhibition of cytokine production.
Changes in periodontal and rheumatological conditions after 2 years in patients with juvenile idiopathic arthritis.
HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta.
Rapid analysis of inflammatory cytokines in cerebrospinal fluid using chip-based immunoaffinity electrophoresis.
Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines.
Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines.
Bryson BD, Rosebrock TR, Tafesse FG, Itoh CY, Nibasumba A, Babunovic GH, Corleis B, Martin C, Keegan C, Andrade P, Realegeno S, Kwon D, Modlin RL, Fortune SM
Nature communications 2019 May 27;10(1):2329
Nature communications 2019 May 27;10(1):2329
Targeting the miR-665-3p-ATG4B-autophagy axis relieves inflammation and apoptosis in intestinal ischemia/reperfusion.
Li Z, Wang G, Feng D, Zu G, Li Y, Shi X, Zhao Y, Jing H, Ning S, Le W, Yao J, Tian X
Cell death & disease 2018 May 1;9(5):483
Cell death & disease 2018 May 1;9(5):483
Exposure to wild-type AAV drives distinct capsid immunity profiles in humans.
Kuranda K, Jean-Alphonse P, Leborgne C, Hardet R, Collaud F, Marmier S, Costa Verdera H, Ronzitti G, Veron P, Mingozzi F
The Journal of clinical investigation 2018 Dec 3;128(12):5267-5279
The Journal of clinical investigation 2018 Dec 3;128(12):5267-5279
DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia.
Johnson DC, Taabazuing CY, Okondo MC, Chui AJ, Rao SD, Brown FC, Reed C, Peguero E, de Stanchina E, Kentsis A, Bachovchin DA
Nature medicine 2018 Aug;24(8):1151-1156
Nature medicine 2018 Aug;24(8):1151-1156
Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in Macrophages.
Karasawa T, Kawashima A, Usui-Kawanishi F, Watanabe S, Kimura H, Kamata R, Shirasuna K, Koyama Y, Sato-Tomita A, Matsuzaka T, Tomoda H, Park SY, Shibayama N, Shimano H, Kasahara T, Takahashi M
Arteriosclerosis, thrombosis, and vascular biology 2018 Apr;38(4):744-756
Arteriosclerosis, thrombosis, and vascular biology 2018 Apr;38(4):744-756
Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airways.
Reuschl AK, Edwards MR, Parker R, Connell DW, Hoang L, Halliday A, Jarvis H, Siddiqui N, Wright C, Bremang S, Newton SM, Beverley P, Shattock RJ, Kon OM, Lalvani A
PLoS pathogens 2017 Sep;13(9):e1006577
PLoS pathogens 2017 Sep;13(9):e1006577
Zinc inhibits high glucose-induced NLRP3 inflammasome activation in human peritoneal mesothelial cells.
Fan Y, Zhang X, Yang L, Wang J, Hu Y, Bian A, Liu J, Ma J
Molecular medicine reports 2017 Oct;16(4):5195-5202
Molecular medicine reports 2017 Oct;16(4):5195-5202
Vitamin D regulates cytokine patterns secreted by dendritic cells to promote differentiation of IL-22-producing T cells.
Sommer A, Fabri M
PloS one 2015;10(6):e0130395
PloS one 2015;10(6):e0130395
Alpha 1-antitrypsin does not inhibit human monocyte caspase-1.
Rahman MA, Mitra S, Sarkar A, Wewers MD
PloS one 2015;10(2):e0117330
PloS one 2015;10(2):e0117330
Inflammasome priming by lipopolysaccharide is dependent upon ERK signaling and proteasome function.
Ghonime MG, Shamaa OR, Das S, Eldomany RA, Fernandes-Alnemri T, Alnemri ES, Gavrilin MA, Wewers MD
Journal of immunology (Baltimore, Md. : 1950) 2014 Apr 15;192(8):3881-8
Journal of immunology (Baltimore, Md. : 1950) 2014 Apr 15;192(8):3881-8
Measurement of interleukin-33 (IL-33) and IL-33 receptors (sST2 and ST2L) in patients with rheumatoid arthritis.
Hong YS, Moon SJ, Joo YB, Jeon CH, Cho ML, Ju JH, Oh HJ, Heo YJ, Park SH, Kim HY, Min JK
Journal of Korean medical science 2011 Sep;26(9):1132-9
Journal of Korean medical science 2011 Sep;26(9):1132-9
IL-17C regulates the innate immune function of epithelial cells in an autocrine manner.
Ramirez-Carrozzi V, Sambandam A, Luis E, Lin Z, Jeet S, Lesch J, Hackney J, Kim J, Zhou M, Lai J, Modrusan Z, Sai T, Lee W, Xu M, Caplazi P, Diehl L, de Voss J, Balazs M, Gonzalez L Jr, Singh H, Ouyang W, Pappu R
Nature immunology 2011 Oct 12;12(12):1159-66
Nature immunology 2011 Oct 12;12(12):1159-66
Resistance of human alveolar macrophages to Bacillus anthracis lethal toxin.
Wu W, Mehta H, Chakrabarty K, Booth JL, Duggan ES, Patel KB, Ballard JD, Coggeshall KM, Metcalf JP
Journal of immunology (Baltimore, Md. : 1950) 2009 Nov 1;183(9):5799-806
Journal of immunology (Baltimore, Md. : 1950) 2009 Nov 1;183(9):5799-806
Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine.
Hu H, Kwun J, Aizenstein BD, Knechtle SJ
Transplantation 2009 Jun 27;87(12):1814-20
Transplantation 2009 Jun 27;87(12):1814-20
Bacterial vaginosis, not HIV, is primarily responsible for increased vaginal concentrations of proinflammatory cytokines.
Mitchell CM, Balkus J, Agnew KJ, Cohn S, Luque A, Lawler R, Coombs RW, Hitti JE
AIDS research and human retroviruses 2008 May;24(5):667-71
AIDS research and human retroviruses 2008 May;24(5):667-71
Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo.
Biancotto A, Iglehart SJ, Lisco A, Vanpouille C, Grivel JC, Lurain NS, Reichelderfer PS, Margolis LB
AIDS research and human retroviruses 2008 Mar;24(3):453-62
AIDS research and human retroviruses 2008 Mar;24(3):453-62
Endogenous IL-32 controls cytokine and HIV-1 production.
Nold MF, Nold-Petry CA, Pott GB, Zepp JA, Saavedra MT, Kim SH, Dinarello CA
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):557-65
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):557-65
Endogenous IL-32 controls cytokine and HIV-1 production.
Nold MF, Nold-Petry CA, Pott GB, Zepp JA, Saavedra MT, Kim SH, Dinarello CA
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):557-65
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):557-65
Effect of serum content and diluent selection on assay sensitivity and signal intensity in multiplex bead-based immunoassays.
Pfleger C, Schloot N, ter Veld F
Journal of immunological methods 2008 Jan 1;329(1-2):214-8
Journal of immunological methods 2008 Jan 1;329(1-2):214-8
Ultrasensitive flow-based immunoassays using single-molecule counting.
Todd J, Freese B, Lu A, Held D, Morey J, Livingston R, Goix P
Clinical chemistry 2007 Nov;53(11):1990-5
Clinical chemistry 2007 Nov;53(11):1990-5
Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1.
Biancotto A, Grivel JC, Iglehart SJ, Vanpouille C, Lisco A, Sieg SF, Debernardo R, Garate K, Rodriguez B, Margolis LB, Lederman MM
Blood 2007 May 15;109(10):4272-9
Blood 2007 May 15;109(10):4272-9
HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1.
Grivel JC, Elliott J, Lisco A, Biancotto A, Condack C, Shattock RJ, McGowan I, Margolis L, Anton P
AIDS (London, England) 2007 Jun 19;21(10):1263-72
AIDS (London, England) 2007 Jun 19;21(10):1263-72
Clinical outcome following acute ischaemic stroke relates to both activation and autoregulatory inhibition of cytokine production.
Emsley HC, Smith CJ, Gavin CM, Georgiou RF, Vail A, Barberan EM, Illingworth K, Scarth S, Wickramasinghe V, Hoadley ME, Rothwell NJ, Tyrrell PJ, Hopkins SJ
BMC neurology 2007 Feb 28;7:5
BMC neurology 2007 Feb 28;7:5
Changes in periodontal and rheumatological conditions after 2 years in patients with juvenile idiopathic arthritis.
Miranda LA, Braga F, Fischer RG, Sztajnbok FR, Figueredo CM, Gustafsson A
Journal of periodontology 2006 Oct;77(10):1695-700
Journal of periodontology 2006 Oct;77(10):1695-700
HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta.
Peng H, Erdmann N, Whitney N, Dou H, Gorantla S, Gendelman HE, Ghorpade A, Zheng J
Glia 2006 Nov 1;54(6):619-29
Glia 2006 Nov 1;54(6):619-29
Rapid analysis of inflammatory cytokines in cerebrospinal fluid using chip-based immunoaffinity electrophoresis.
Phillips TM
Electrophoresis 2004 Jun;25(10-11):1652-9
Electrophoresis 2004 Jun;25(10-11):1652-9
Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines.
Copeland S, Siddiqui J, Remick D
Journal of immunological methods 2004 Jan;284(1-2):99-106
Journal of immunological methods 2004 Jan;284(1-2):99-106
Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines.
Copeland S, Siddiqui J, Remick D
Journal of immunological methods 2004 Jan;284(1-2):99-106
Journal of immunological methods 2004 Jan;284(1-2):99-106
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