Tissue expression
Cell line expression
Protein structure
PTGS1
Prostaglandin-endoperoxide synthase 1COX1, PGHS-1, PTGHS
This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Top validated antibodies |
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Boster Biological Technology | ![]() |
2 references | Monoclonal |
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Invitrogen Antibodies | ![]() |
2 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Proteintech Group | ![]() |
22 references | Polyclonal |
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Novus Biologicals | ![]() |
Monoclonal |
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