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Cell line expression
Protein structure
TBX21
T-box transcription factor 21T-bet, TBLYM
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  13700-1-AP |
24 references | Polyclonal |
WB
EL
IP
IHC
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| Invitrogen Antibodies | 14-5825-37 |
106 references | Monoclonal |
WB
ICC
IP
IHC
OA
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| Cell Signaling Technology, Inc | 13232 |
Monoclonal |
WB
ICC
IP
IHC
FC
ChIP
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| LSBio | LS-B10130 |
Polyclonal |
WB
EL
ICC
IHC
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| R&D Systems | MAB5385 |
3 references | Monoclonal |
WB
ICC
FC
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