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Protein structure
CHD4
Chromodomain helicase DNA binding protein 4Mi-2b, Mi2-BETA
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Top validated antibodies |
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| Novus Biologicals |  NBP2-50163 |
1 references | Monoclonal |
WB
EL
ICC
IP
IHC
FC
ChIP
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| Proteintech Group | 14173-1-AP |
5 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| GeneTex | GTX124186 |
3 references | Polyclonal |
WB
ICC
IP
IHC
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| Invitrogen Antibodies | 1108-MSM1-P0 |
Monoclonal |
WB
EL
ICC
IHC
FC
IEM
OA
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| NSJ Bioreagents | V7676 |
Monoclonal |
WB
EL
ICC
IHC
OA
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