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Protein structure
CHD3
Chromodomain helicase DNA binding protein 3Mi-2a, Mi2-ALPHA, ZFH
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals |  NBP1-51593 |
1 references | Monoclonal |
WB
EL
ICC
IHC
FC
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| antibodies-online | ABIN1106677 |
2 references | Monoclonal |
WB
ICC
IHC
FC
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| OriGene | AM06458SU-N |
Monoclonal |
WB
EL
ICC
IHC
FC
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| GeneTex | GTX83232 |
Monoclonal |
WB
EL
ICC
IHC
FC
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| Proteintech Group | 25335-1-AP |
1 references | Polyclonal |
WB
EL
ICC
IHC
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