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Protein structure
MAP3K11
Mitogen-activated protein kinase kinase kinase 11MEKK11, MLK3, PTK1, SPRK
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  11996-1-AP |
7 references | Polyclonal |
WB
EL
ICC
IHC
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| LSBio | LS-B10053 |
Monoclonal |
WB
EL
IHC
|
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| Abnova Corporation | H00004296-M02 |
Monoclonal |
WB
EL
IHC
PLA
|
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| Novus Biologicals | H00004296-M02 |
Monoclonal |
WB
EL
IHC
PLA
|
||
| NovoPro Bioscience Inc. | 112679 |
Polyclonal |
WB
EL
ICC
IHC
|
||
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