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Cell line expression
Protein structure
ERCC6L
ERCC excision repair 6 like, spindle assembly checkpoint helicaseFLJ20105, PICH, RAD26L
This gene encodes a member of the SWItch/Sucrose Non-Fermentable (SWI/SNF2) family of proteins, and contains a SNF2-like ATPase domain and a PICH family domain. One distinguishing feature of this SWI/SNF protein family member is that during interphase, the protein is excluded from the nucleus, and only associates with chromatin after the nuclear envelope has broken down. This protein is a DNA translocase that is thought to bind double-stranded DNA that is exposed to stretching forces, such as those exerted by the mitotic spindle. This protein associates with ribosomal DNA and ultra-fine DNA bridges (UFBs), fine structures that connect sister chromatids during anaphase at some sites such as fragile sites, telomeres and centromeres. This gene is required for the faithful segregation of sister chromatids during mitosis, and the ATPase activity of this protein required for the resolution of UFBs before cytokinesis. [provided by RefSeq, May 2017]
Top validated antibodies |
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| Novus Biologicals |  H00054821-D01P |
9 references | Polyclonal |
WB
ICC
IHC
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| antibodies-online | ABIN565778 |
4 references | Monoclonal |
WB
EL
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| Abnova Corporation | H00054821-M01 |
2 references | Monoclonal |
WB
EL
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| Proteintech Group | 15688-1-AP |
3 references | Polyclonal |
WB
EL
|
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| Invitrogen Antibodies | H00054821-M01 |
Monoclonal |
WB
EL
OA
|
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