Tissue expression
Cell line expression
Protein structure
SPRY4
Sprouty RTK signaling antagonist 4This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP-RAS. Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants. [provided by RefSeq, Jun 2014]
Top validated antibodies |
|||||
| Proteintech Group | 6 references | Polyclonal |
|
||
| Biorbyt | Recombinant |
|
|||
| Invitrogen Antibodies | Polyclonal |
|
|||
| NSJ Bioreagents | Polyclonal |
|
|||
| LSBio | Polyclonal |
|
|||